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Advancing Research to Develop Improved Measures and Methods for Understanding Multimorbidity (R01 Clinical Trial Optional)

- Availability, quality, and utility of data and measures for capturing multimorbidity or multiple chronic conditions (MCCs)

- Discovery, development, and/or evaluation of MCC measures/tools that reflect longitudinality and life course diversity of multimorbidity

- Mechanistic discovery of shared MCC pathways using animal models

- Identification and initial biological, analytical, and clinical evaluation of MCC shared signatures

- Patient-focused studies capturing patient reports, functional limitations, and quality of life

- Analytic approaches suitable for multimorbidity data and target populations

- Utilization of multimorbidity data available in electronic health record (EHR) systems

- Use of existing data and data linkages for exploring new co-occurring MCC research questions

- Shared mechanisms and innovative interventions for addressing MCCs

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88%

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