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Ancillary Studies to the NIDDK Inflammatory Bowel Disease Genetics Consortium (R01 Clinical Trial Not Allowed)

List of required information for application:

1. Research proposal describing the specific aims and objectives of the Ancillary Study.

2. Description of the proposed methods and experimental approach for causal variant identification and/or functional characterization of effector genes within IBD risk loci.

3. Justification for the need to expand the number of IBD susceptibility loci, causal variants, and effector genes under investigation.

4. Explanation of how the proposed Ancillary Study will contribute to the understanding of the genetic architecture of IBD phenotypes and elucidate the biological mechanisms influencing IBD pathophysiology and clinical course.

5. Description of the resources, including subjects, samples, and datasets, that will be utilized from the IBDGC.

6. Statement confirming that the proposed Ancillary Study will not duplicate studies either ongoing or already completed by the IBDGC.

7. Estimated budget for the proposed Ancillary Study, including personnel, supplies, and any other necessary resources.

8. Timeline and milestones for the completion of the proposed Ancillary Study.

9. Description of any collaborations or partnerships that will be involved in the execution of the proposed Ancillary Study.

10. List of references relevant to the proposed research.

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Funding Amount

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Eligible Applicants

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88%

Approval rating across all Canadian funding programs

93%

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