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Animal Models for Hepatitis B and C (R01 Clinical Trial Not Allowed)

- Name of the Principal Investigator (PI)

- Contact information of the PI (including email address and phone number)

- Institutional affiliation of the PI

- Project title

- Project summary/abstract

- Research plan outlining the specific aims, methods, and timeline of the proposed research

- Justification for the need of convenient small animal models or surrogate virus-host systems in the study of HBV and/or HCV

- Description of how the proposed research will support infection and replication of HBV and/or HCV

- Description of how the proposed research will lead to the outcomes of clearance and persistence of HBV and/or HCV

- Description of the use of xenotransplantation models and the engraftment of human liver cells and human immune systems

- Budget proposal, including itemized costs and justification for each expense

- Data management plan for handling and analyzing research data

- Plans for dissemination of research findings

- Statement of compliance with ethical guidelines for animal research, if applicable

- CV or biosketch of the PI and other key personnel involved in the project

- Letters of support or collaboration from partnering institutions or individuals, if applicable.

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Funding Amount

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88%

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93%

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