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Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)

List of required information for application:

1. Description of the molecular/cellular/imaging markers or biomarkers being studied

2. Description of the assay(s) that have been analytically validated for the intended clinical use of the markers or biomarkers

3. Plan for the acceleration and adoption of the markers and assays for cancer detection, diagnosis, prognosis, monitoring, prediction of response or resistance to treatment, markers for cancer prevention and control, as well as pharmacodynamic markers and markers of toxicity

4. Description of the multi-marker assays, including immune markers, that will be developed and validated simultaneously

5. Plan for the clinical validation of established assays using specimens from retrospective or prospective clinical trials or studies

6. Description of how the validated assays will be used in other trials, observational studies, or population studies

7. Description of efforts to harmonize clinical laboratory tests and investigation into the performance and reproducibility of assays across multiple clinical laboratories

8. Plan for multi-disciplinary interaction and collaboration among scientific investigators, oncologists, statisticians, and clinical laboratory scientists

9. Explanation of how the project focuses on the validation of assays rather than early-stage development of technology or the conduct of clinical trials

10. Timeline for the validation of the assays and integration into clinical trials or studies as investigational assays.

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Funding Amount

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Eligible Applicants

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Eligible Activities

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Deadline to Apply

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88%

Approval rating across all Canadian funding programs

93%

Average time savings to our clients, compared to
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