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BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)

List of Required Information for Application:

1. Title of the proposed project.

2. Project summary/abstract.

3. Project narrative, including the problem statement, research objectives, and significance of the study.

4. Detailed description of the experimental protocol and methods to be used.

5. List of key personnel involved in the project, including their roles and qualifications.

6. Description of the interdisciplinary collaboration within the research team.

7. Explanation of how the project addresses the fundamental barriers in human neuroscience research.

8. Overview of the feasibility, proof-of-principle, and early-stage development of the proposed research.

9. Discussion on the potential impact of the research and its contribution to the field.

10. Statement of the theoretical constructs and mechanistic models guiding the research approach.

11. Description of how the project maximizes opportunities for innovative in vivo neuroscience research.

12. Plan for joining the consortium working group and contribution to identifying consensus standards of practice.

13. Discussion on the collection and provision of data for ancillary studies.

14. Plan for aggregating and standardizing data for dissemination among the wider scientific community.

15. Budget proposal, including details of how the grant funds will be allocated.

16. Proposed timeline for the project, including milestones and deliverables.

17. Potential risks and mitigation strategies associated with the invasive surgical procedures.

18. Discussion on the neuroethical considerations involved in the research.

19. Previous relevant research experience or preliminary data, if applicable.

20. References and citations supporting the proposed research.

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88%

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93%

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