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Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)

1. Project title

2. Project summary/abstract

3. Applicant organization and contact information

4. Principal investigator's name, contact information, and qualifications

5. Collaborating institutions or partners, if applicable

6. Budget proposal and itemized expenses

7. Timeline for project completion

8. Description of the proposed animal models to be developed or improved

9. Description of the biological materials to be characterized or enhanced

10. Description of the novel technologies to be developed or utilized

11. Explanation of how the proposed project aligns with the Office of Research Infrastructure Programs (ORIP) trans-NIH mission

12. Explanation of the potential broad applications of the proposed project to multiple NIH Institutes or Centers (ICs)

13. Explanation of how the proposed studies explore multiple body systems or evaluate diseases that impact multiple body systems

14. Justification for the importance and relevance of the proposed project to the field of biomedical research

15. Description of any existing animal models, biological materials, or technologies that will be utilized in the project

16. Plan for the dissemination of project findings and results

17. Any ethical considerations or Institutional Animal Care and Use Committee (IACUC) approval, if applicable

18. List of references and supporting documents, if applicable

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