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Exploratory/Developmental Grants on Lifestyle Medicine Research Related to the World Trade Center Health Program (R21)

1. Full name of the applicant.

2. Contact information of the applicant (email, phone number).

3. Project title.

4. Brief summary of the proposed research project.

5. Description of how the proposed research addresses diagnostic or treatment uncertainty for individuals receiving monitoring and/or treatment under subtitle B of the James Zadroga 9/11 Health and Compensation Act.

6. Inclusion criteria for enrolled WTC responders and certified-eligible WTC survivors in the research project.

7. Explanation of how lifestyle medicine is applicable to managing and reversing WTC-related health conditions.

8. Details of the six pillars of lifestyle medicine: nutrition and diet, sleep hygiene, stress management and positive psychology, physical activity, social connectedness, and avoidance of substance misuse.

9. Explanation of how lifestyle medicine can limit disease progression, prevent additional chronic diseases, and improve health outcomes, well-being, quality of life, and member satisfaction.

10. Description of the scope and objectives of the proposed lifestyle medicine research.

11. Explanation of how the research project aims to achieve a suitable mix of projects and interventions related to sustainable health behaviors and lifestyle factors.

12. Discussion of how sustainable health behaviors and lifestyle factors impact quality of life, disease progression and recurrence, survival, adverse events, and other health-related outcomes among WTC Health Program members.

13. Explanation of how the proposed research is in the early and conceptual stages, assessing the feasibility of novel areas of investigation.

14. Description of how the proposed research has the potential to enhance the effectiveness of treatment and diagnostic practice.

15. Discussion of how the proposed research may lead to breakthroughs in a particular area or the development of novel techniques, agents, methodologies, models, or applications with a major clinical impact.

16. Overview of the expected research approaches and the availability (or lack) of preliminary data.

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