Tab 1 – Application Information Submission of application information includes assignment of primary and secondary research classification codes, which may be found at https://ebrap.org/eBRAP/public/ Program.htm. Applicants are strongly encouraged to review and confirm the codes prior to making their selection. • Tab 2 – Application Contacts Enter contact information for the PI. Enter the organization’s Business Official responsible for sponsored program administration (the “person to be contacted on matters involving this application” in Block 5 of the Grants.gov SF424 Research & Related Form). The Business Official must be either selected from the eBRAP list or invited in order for the preapplication to be submitted. Select the performing organization (site at which the PI will perform the proposed work) and the contracting organization (organization submitting on behalf of the PI, which corresponds to Block 5 on the Grants.gov SF424 Research & Related Form), and click on “Add Organizations to this Pre-application.” The organization(s) must be either selected from the eBRAP drop-down list or invited in order for the pre-application to be submitted. It is recommended that PIs identify an Alternate Submitter in the event that assistance with pre-application submission is needed. • Tab 3 – Collaborators and Key Personnel Enter the name, organization, and role of all collaborators and key personnel associated with the application. FY23 MRP Programmatic Panel members should not be involved in any pre-application or application. For questions related to panel members and pre-applications or applications, refer to Section II.H.2.c, Withdrawal, or contact the CDMRP Help Desk at help@eBRAP.org or 301-682-5507. • Tab 4 – Conflicts of Interest List all individuals other than collaborators and key personnel who may have a conflict of interest in the review of the application (including those with whom the PI has a personal or professional relationship). • Tab 5 – Pre-Application Files Note: Upload documents as individual PDF files unless otherwise noted. eBRAP will not allow a file to be uploaded if the number of pages exceeds the limit specified below. o Preproposal Narrative (one-page limit): The Preproposal Narrative page limit applies to text and non-text elements (e.g., figures, tables, graphs, photographs, diagrams, chemical structures, drawings) used to describe the project. Inclusion of URLs (uniform DOD FY23 Melanoma Idea Award 14 resource locators) that provide additional information to expand the Preproposal Narrative and could confer an unfair competitive advantage is prohibited and may result in administrative withdrawal of the pre-application. The Preproposal Narrative should include the following: – Describe the rationale and hypothesis and how these support the study’s objectives and specific aims. Describe how the methodology and experimental design support the project’s goals. Preliminary data are discouraged. – Explain how the project is beyond an incremental advancement and not an extension of previously published findings or theories, or a continuation of an established research program in the applicant’s laboratory. Describe how the project is innovative (i.e., leads to a new paradigm, challenges current paradigms, introduces novel concepts or agents, or exhibits other uniquely creative qualities). – State the FY23 MRP Focus Area(s) in Section II.A.1 to be studied and describe how the research, assuming success, will make an impact. o Pre-Application Supporting Documentation: The items to be included as supporting documentation for the pre-application must be uploaded as individual files and are limited to the following: – References Cited (one-page limit): List the references cited (including URLs if available) in the Preproposal Narrative using a standard reference format that includes the full citation (i.e., author[s], year published, reference title, and reference source, including volume, chapter, page numbers, and publisher, as appropriate). – List of Abbreviations, Acronyms, and Symbols: Provide a list of abbreviations, acronyms, and symbols used in the Preproposal Narrative. – Key Personnel Biographical Sketches (five-page limit per individual): All biographical sketches should be uploaded as a single combined file. Biographical sketches should be used to demonstrate background and expertise through education, positions, publications, and previous work accomplished. • Tab 6 – Submit Pre-Application This tab must be completed for the pre-application to be accepted and processed.
