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National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders or Alcohol Use Disorder (U19 Clinical Trial Optional)

1. Proposed candidate agents or neurostimulation approaches for the treatment of mental disorders, substance use disorders (SUDs), or alcohol use disorder (AUD).

2. Description of the rational basis for the proposed candidate agents or neurostimulation approaches.

3. Preclinical development plan for the candidate agents or neurostimulation approaches.

4. Proof of concept (PoC) testing plan for the candidate agents or neurostimulation approaches.

5. Description of how the proposed research will contribute to the advancement of treatment options for mental disorders, SUDs, or AUD.

6. Description of how the proposed research will contribute to the characterization or validation of drug/device targets.

7. Evidence of partnership between academia and industry, if applicable.

8. Description of the research program's major objective, basic theme, or program goal.

9. Explanation of the need for a broadly based, multidisciplinary, and long-term approach to achieve the research program's objective.

10. Justification for support of a research program with multiple projects rather than a discrete, specified project.

11. Budget plan for the research program, including estimated costs for each project.

12. Timeline for the research program, including milestones and expected completion dates for each project.

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Funding Amount

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Eligible Applicants

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88%

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93%

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