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NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

List of required information for application:

1. Title of the proposed project

2. Research and scientific premise justifying the need for further clinical testing of the natural product

3. Description of the natural product being studied (botanicals, dietary supplements, or probiotics)

4. Detailed study design, including interventions, outcome measures, and participant population

5. Justification for the chosen biological signature(s) and their relevance to functional or clinical outcomes in the patient population

6. Plans to replicate the impact of the natural product on the biological signature(s) in humans

7. Strategies to optimize the delivery of the natural product, such as examining different doses or formulations

8. Potential combination of the natural product with another treatment approach known to impact the same biological signature

9. Target population selection and rationale for their responsiveness to the natural product

10. Hypotheses to be tested and milestones to be achieved in the proposed clinical trial

11. Alignment of the proposed research with the research priorities and mission of NCCIH

12. Description of how the proposed project will accelerate the translation of emerging basic science findings into early stage clinical testing

13. Statement confirming that the proposed trial is not an efficacy or effectiveness trial, nor a trial for cancer treatment or prevention.

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Funding Amount

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Eligible Applicants

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Eligible Activities

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Deadline to Apply

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88%

Approval rating across all Canadian funding programs

93%

Average time savings to our clients, compared to
businesses that apply for funding in-house
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