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Notice of Intent to Publish a Funding Opportunity Announcement for Improving Uptake and Use of the Dapivirine Vaginal Ring for HIV Prevention (R21 Clinical Trial Optional)

List of required information for application:

1. Applicant details: Name, contact information, institutional affiliation, and any relevant credentials or qualifications.

2. Project title: A clear and concise title that reflects the focus and objectives of the proposed research.

3. Project summary: A brief summary or abstract of the proposed research, outlining the research question, objectives, and potential impact.

4. Project description: Detailed description of the research plan, including the specific aims, methodology, timeline, and expected outcomes. This should also include how the research aims to advance understanding of multilevel facilitators and barriers to use of the dapivirine vaginal ring, develop interventions to support uptake and correct and persistent use of the vaginal ring, and test implementation strategies for optimal delivery of the vaginal ring.

5. Research team: Information about the key personnel involved in the project, their roles, and expertise relevant to the research.

6. Budget: A detailed budget plan, including estimated costs for personnel, equipment, supplies, travel, and any other necessary expenses. This should align with the funding limits and guidelines specified in the FOA.

7. Research timeline: A timeline or schedule indicating the key milestones, activities, and duration of the proposed research.

8. Institutional support: Documentation or statements of institutional support indicating the resources, facilities, and infrastructure available to support the proposed research.

9. Data management plan: A plan for data collection, storage, analysis, and sharing, addressing issues such as data security, privacy, and compliance with relevant regulations and policies.

10. Ethical considerations: Description of the ethical considerations and measures to be taken to protect human subjects (if applicable) and ensure compliance with ethical guidelines and regulations.

11. References: A list of relevant references and citations to support the proposed research and demonstrate familiarity with existing literature in the field.

12. Collaborations: Details of any collaborations or partnerships with other institutions or organizations that will enhance the research project.

13. Previous experience: Information on any previous experience or expertise in conducting similar research or relevant projects.

14. Impact and dissemination plan: Description of how the research findings will be disseminated, potential impact on the field, and plans for knowledge translation or implementation of the findings.

15. Compliance: Assurance of compliance with all relevant regulations, policies, and guidelines, including research involving human subjects, animal studies, biohazard safety, etc.

16. Letters of support: Letters of support or collaboration from partnering institutions, organizations, or stakeholders that indicate their

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