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Pre-application: Opportunities for Collaborative Research at the NIH Clinical Center (X02 Clinical Trial Optional)

List of Required Information for Application:

1. Project Title: Provide a clear and concise title for the proposed research project.

2. Research Objectives: Clearly state the main goals and objectives of the proposed research, including specific disease processes, therapeutic interventions, diagnostics, or prevention strategies to be studied.

3. Collaborative Team: Identify and provide background information on the members of the collaborative research team, including the principal investigators from both the NIH intramural and extramural institutions.

4. Research Plan: Present a detailed research plan that outlines the study design, methodology, and data analysis techniques to be employed in the project.

5. Significance: Describe the significance of the proposed research and how it aligns with the research interests and priorities of the participating NIH Institutes/Centers (ICs).

6. Innovation: Highlight any novel or innovative aspects of the research project that distinguish it from existing studies in the field.

7. Timeline: Provide a clear timeline for the completion of the proposed research activities, including specific milestones and deliverables.

8. Budget: Develop a detailed budget that outlines the necessary funding required to support the proposed research, including personnel, equipment, supplies, and travel expenses.

9. Collaboration Plan: Describe the specific plans for collaboration between the NIH intramural and extramural investigators, including communication strategies and division of responsibilities.

10. Facilities and Resources: Provide information on the resources and facilities available at both the NIH Clinical Center and the extramural institution that will be utilized for the research project.

11. Ethical Considerations: Address any ethical considerations or potential risks associated with the proposed research, including human subjects, animal experimentation, or any other relevant ethical concerns.

12. Expected Outcomes: Discuss the potential impact and expected outcomes of the research project, including how it will contribute to the advancement of translational science and improve health outcomes.

13. References: Include a list of relevant references cited throughout the application to support the rationale and background of the proposed research.

14. Supporting Documents: Attach any required supporting documents, such as letters of collaboration, biosketches of key personnel, and any other additional information requested in the application guidelines.

Note: The specific information required may vary depending on the application guidelines provided by the funding agency. It is important to review and follow the instructions provided in the application package.

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