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Preclinical Studies to Characterize the Impact of Toxicants on Brain Aging and Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (U01 Clinical Trial Not Allowed)

- Name of the research project

- Research objectives 

- Description of the toxicants being studied

- Description of the mouse models of Late Onset AD (LOAD)

- Details of the cross-sectional/longitudinal multi-modal phenotyping methods to be used

- Criteria for early and mid-life exposure to be considered

- Information on the genetic diversity and sex-differences in relation to exposure-related AD outcomes.

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