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Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3 Clinical Trial Not Allowed)

- Grant application form

- Project title

- Applicant information (name, contact information, academic affiliations, CV, etc.)

- Research plan summary

- Overview of the study objectives and how they align with the mission and research interests of the NINDS

- Description of the proposed study design, including the use of prospective observational comparative effectiveness research (CER)

- Clear statement of the research questions being addressed

- Explanation of how the study will evaluate preventive strategies, diagnostic approaches, or interventions related to drugs, biologics, devices, surgeries, behavioral therapies, and rehabilitation therapies

- Cost-effective data collection plan that is meaningful to current clinical practice

- Timeline and milestones for the planning phase (UG3) and the observational study phase (UH3)

- Description of the scientific and operational planning activities to be conducted in the UG3 phase, including feasibility and acceptability of data collection, storage, and planned analyses, as well as recruitment and retention strategies, case report forms, data management system, and quality management tools

- Justification for the transition from the UG3 phase to the UH3 phase

- Budget outline for the entire project, including both UG3 and UH3 phases

- Any potential conflicts of interest or ethical considerations that may arise during the study

- References to support the research proposal and demonstrate familiarity with current literature in the field of clinical neurosciences

- Any additional supporting documents or data that are relevant to the application.

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Funding Amount

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Eligible Applicants

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Eligible Activities

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Deadline to Apply

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