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Pulmonary Outcomes and Sequelae after Treatment-TB (POST-TB) (R01 Clinical Trial Optional)

List of required information for application:

1. Project Title: Provide a clear and concise title for the proposed research project.

2. Project Summary: Summarize the objectives, methods, and expected outcomes of the research project.

3. Project Description: Provide a detailed description of the proposed research, including the study design, data collection methods, and analysis plan.

4. Specific Aims: Clearly state the specific aims or research questions that the project aims to address.

5. Background and Significance: Explain the rationale and importance of the research project in the context of the long-term cardiopulmonary sequelae following TB treatment.

6. Experimental Approach: Describe the approach, methods, and procedures that will be used to collect and analyze data for the research project.

7. Expected Outcomes: Provide a clear and realistic description of the expected outcomes, including potential contributions to the field of TB research and public health.

8. Justification for Additional Testing and Data Collection: Explain why additional testing and data collection are needed in existing cohorts of adult and/or pediatric TB participants and how it will contribute to better characterizing adverse outcomes and morbidity associated with TB disease post-treatment.

9. Inclusion/Exclusion Criteria: Specify the criteria for selecting participants for the research project, including age, gender, TB diagnosis, and HIV status.

10. Timelines and Milestones: Provide a timeline for the research project, including specific milestones and deliverables.

11. Budget and Justification: Provide a detailed budget for the research project, including personnel, equipment, supplies, and other expenses. Justify the budget based on the proposed activities and expected outcomes.

12. Research Team: Provide information on the principal investigator(s), co-investigators, and other key personnel involved in the research project, including their qualifications and roles.

13. Ethical Considerations: Describe the ethical considerations and protections that will be implemented to ensure the rights and well-being of research participants.

14. Dissemination Plan: Outline the plan for disseminating the research findings, including any publications, presentations, or other knowledge translation activities.

15. References: Include a list of relevant references cited in the application.

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