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The Blood and Marrow Transplant Clinical Trials Network - Data Coordinating Center (U24 Clinical Trial Not Allowed)

- Applicant's contact information (name, address, phone number, email)

- Project title

- Project abstract

- Project duration

- Description of the proposed clinical trials network and its goals

- Description of the rare and difficult to treat non-malignant blood diseases and hematological malignancies targeted by the network

- Overview of the novel cell therapy and hematopoietic cell transplantation approaches to be evaluated

- Description of the Data Coordinating Center (DCC) and its role in supporting the network

- Description of the core clinical sites and their role in supporting the network

- Details of the funds requested for the initiative

- Plan for collaborating with RO I-funded grantees, industry, and foundations for additional studies and trials

- Explanation of why the duration of most HCT and CT trials exceeds 5 years

- Plan for monitoring patient accrual and addressing rare patient populations

- Description of the complex cell manufacturing processes involved

- Description of composite endpoints such as disease-free survival and chronic graft versus-host disease free survival

- Budget breakdown and justification for requested funds

- Plan for evaluating the success and impact of the funded activities

- Any additional supporting documents or letters of support.

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Funding Amount

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Eligible Applicants

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Eligible Activities

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Deadline to Apply

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88%

Approval rating across all Canadian funding programs

93%

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